A gene may protect its carrier against a range of cancers, according to new tests.
Two different variants of the B-MYB gene found in close to 50% of the world's population are less likely in people suffering from cancer, the journal Nature reports.
The Institute of Child Health's Dr Arturo Sala said it might show to be a "key player" in cancer.
Charity Cancer Research UK mentioned that more research will likely make clear how it will likely help prevent the cancer.
More indepth research had already shown B-MYB having a role in the spread and development of the disease.
It has been found to be over-active in numerous cancers.
The latest exams tested over 400 people with either colon cancer, a brain tumour known as neuroblastoma, also known as chronic myeloid leukaemia.
Their type of the B-MYB gene was tested and compared to the versions found in 230 "controls" - people who volunteered with no known cancer.
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