The Number of Cells that Fix Fat Remains Constant Throughout Life.
PARIS - The number of specialized cells in the storage of lipids, or adipocytes, defined in childhood, remains constant throughout life, according to a study appeared in the British scientific journal "Nature". They are renewed by almost 10% per year.
A team of researchers led by Kirsty Spalding of the Karolinska Institute in Stockholm, concluded that the two main determinants of obesity are the number of adipocytes and their size.
However, by investigating cells originating from liposuction or abdominal reconstruction, the researchers were able to establish that after childhood, the number of adipocytes remains constant in grown-ups, with a regular renewal of about 10% annually.
Cell Substitution
"The total number of fat cells in the body is stable since the production of new cells is offset by an equal loss of cells that die," said Peter Arner, the co-author of the research.
Therefore, a reduction of weight in adulthood only diminishes the mass of cells, which is quickly recovered by new ones.
"The new fat cells that lay down fat which is generated during and after weight reduction need to quickly grow in lipids," notes Peter Arner. "This would explain, at least partially, why it's so difficult to maintain the weight one has reached after a reducing diet."
Age and Treatment of Obesity
The researchers also found that adipocytes begin to develop earlier in the obese (around the age of 2 years) than in people with normal weight (between 5 and 6 years), moreover, the raise in weight is two times faster for the obese but it also stops earlier (16 years against 18 years in others).
This study confirms the statistics showing that the majority of adults are obese since childhood, only 10% of children with normal weight become obese when growing up and more than three-quarters of obese children have been keeping this obesity.
These data, dealing with the number of adipocytes determined in childhood and the regular-renewal of these cells should, according to researchers, make it possible to define new targets for obesity therapy , in childhood by acting to limit the number of adipocytes, or in adulthood, by decreasing the substitution of dead cells with new ones.
Women, Age and Obesity
Women in their Thirties
The waist is tending to grow rapidly, especially, for females between 30 and 40 years. This could indicate that obesity in middle-aged and mature women is more widespread than previously assumed, wrote the authors of a study published in the specialist journal “BMC Public Health”.
It is possible that experiencing several pregnancies results in obesity, according to Dr. Marques-Vidal. But this is a hypothesis that has to be scientifically examined. There is, therefore, no recommendation for specific groups within the population. “Preventive measures should apply to the entire population” says the doctor.
Herbal Treatment against Overweight
Herbal medicine remains certainly the best way to accomplish a reducing weight diet. Over-weight has two main causes, the first is an uncontrolled appetite and the second is low metabolic rates related to a food absorption dysfunction. The function of herbal drugs would be to suppress the voracious appetite or to boost the metabolism in order to increase metabolic rates in the safest way ever. Self-conviction is also very important to control the huge appetite, if you are not mentally ready to begin a diet, the whole operation is utterly useless. You may be more helpless towards obesity caused by low metabolic rates because you may not be a big eater but involuntary fat.
Herbal drugs will enhance your food absorption through increasing your metabolic rates with no one drawback. Thus, herbal weight loss appears to be the safer way to go through a reducing weight program.
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